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有音乐指挥才能的唐氏综合征患者的脑结构和神经心理测查个案研究
  • 摘要

    目的:探究1例有音乐指挥才能的唐氏综合征患者的脑结构和认知功能特点,以期有助于进一步理解唐氏综合征的病理机制.方法:以患有唐氏综合征的知名音乐指挥H先生为研究对象,进行染色体检查、神经学检查、计算机断层扫描(CT)检查和磁共振成像(MRI)检查,用瑞文氏智商测试量表和童话故事测验(FTT)进行心理行为测查,由音乐专业人士评价其音乐指挥能力(范围0~10分,10分代表相应能力最高.包括音乐节奏感、音乐的情绪表现力及对观众的感染力).详细了解其成长史.结果:H先生被证实是唐氏综合征患者;神经学检查除视力较差外无特殊异常;脑结构成像检查显示其小脑萎缩、侧脑室扩张、仓白球区钙化.瑞文氏智商测试得分33分,FTT的T分为50分.H先生的音乐节奏感(8.5±1.2)分、音乐的情绪表现力(8.2±1.2)分、对观众的感染力(9.3±0.8)分.经H先生从小在某乐团的环境中成长,很小就学指挥音乐.结论:H先生脑结构发育不良、智商低,但从小经过音乐训练,其音乐指挥才能突出.提示早期训练能使唐氏综合征患者某方面才能得到显著提高.

  • 作者

    崔恒武  张建新  狄海波  章士正  陈宜张  CUI Heng-Wu  ZHANG Jian-Xin  DI Hai-Bo  ZHANG Shi-Zheng  CHEN Yi-Zhang 

  • 作者单位

    江苏大学临床医学院,江苏镇江,212001/中国科学院心理研究所,北京,100101/杭州师范大学,杭州,310018/浙江大学医学院附属邵逸夫医院放射科,杭州,310016/第二军医大学神经科学研究所,上海,200433

  • 刊期

    2013年2期 ISTIC PKU CSSCI

  • 关键词

      唐氏综合征  音乐  情绪  个案研究 

参考文献
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