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仲胺配合物的合成、晶体结构及与DNA作用的研究
  • 摘要

    合成了一种新颖三齿配体(L),N-(4-甲基苯)-N’-(2-(4-甲基苯氨基)乙基)乙烷-1,2-二胺,并制备了它的四种过渡金属配合物,结合元素分析、红外、1 HNMR和摩尔电导,确定配合物的组成为[ML(NO3)2](M=CuⅡ,CoⅡ,NiⅡ,ZnⅡ).用X-ray单晶衍射解析了Zn-L和Ni-L的单晶结构.通过紫外、荧光光谱研究了这四种金属配合物与小牛胸腺DNA的相互作用,根据结果推断出配合物与DNA的作用方式可能均为静电结合.Cu-L,Co-L,Ni-L,Zn-L与DNA的结合常数分别为:3.34×104,7.65×103,2.15×104,2.40× 104.

  • 作者

    胡琴  戴雪芹  张岐  崔艳丽  贾春满  曹本男  HU Qin  DAI Xue-qin  ZHANG Qi  CUI Yan-li  JIA Chun-man  CAO Ben-nan 

  • 作者单位

    海南大学材料与化工学院,海南海口,570228

  • 刊期

    2012年4期 ISTIC PKU

  • 关键词

    配合物  单晶结构  DNA  静电结合  结合常数 

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